1. Remove strip from pouch. Twist strip to loosen and separate slits prior to use. 2. After washing your face, thoroughly wet your nose. The strip won't stick on a dry nose. 3. Dry hands. Peel strip off plastic liner. Apply to nose area, smooth side down, pressing down to ensure good contact with skin. 4. Let dry for about 10-15 minutes until stiff to the touch - like papier-mâché. 5. Slowly and carefully peel off starting at edges, pulling toward center. 6. For best results, do not use more often than once every three days.